N-Acetyl Semax (30mg)

N-Acetyl Semax is an acetylated synthetic analogue of Semax — a heptapeptide derivative of the ACTH (4-10) fragment developed at the Institute of Molecular Genetics, Russian Academy of Sciences. The N-acetyl modification confers significantly enhanced metabolic stability compared to the parent Semax molecule. Like Selank, Semax holds regulatory approval in Russia as a nootropic and neuroprotective agent — placing it in the rare category of research peptides with a formal clinical approval pathway in any jurisdiction.

N-Acetyl Semax Research Background

BDNF upregulation: The most consistently replicated finding in Semax research is potent upregulation of BDNF (Brain-Derived Neurotrophic Factor) and its receptor TrkB. BDNF is the primary neurotrophin governing neuronal survival, synaptic plasticity, and long-term memory formation. Studies in rodent models document rapid and sustained BDNF elevation following Semax administration — with broad implications for neuroplasticity and cognitive function research.

Cognitive enhancement research: Animal studies have examined Semax’s effects on learning, memory consolidation, and attention, documenting improvements in spatial navigation and working memory tasks. The Russian clinical research programme has investigated Semax in human subjects for cognitive enhancement and recovery from ischaemic stroke.

Neuroprotection: Semax has been studied in models of cerebral ischaemia, traumatic brain injury, and neurodegeneration, with research documenting reduced neuronal apoptosis and preserved cognitive function in rodent stroke models.

Dopaminergic system: Studies have examined Semax’s interactions with dopaminergic and serotonergic pathways, documenting modulation of dopamine receptor expression and dopamine metabolism in prefrontal cortical regions.

N-Acetyl vs standard Semax: The acetyl modification significantly slows enzymatic degradation, extending the research compound’s activity window. N-Acetyl Semax is the preferred form for most research applications requiring sustained CNS activity.

Reconstitution & Storage

Reconstitute with BAC water or sterile saline. Concentration: 0.5mg/ml to 1mg/ml.
Lyophilised: 2–8°C | Reconstituted: 2–8°C up to 21 days | Long-term: -20°C

Peptide Reconstitution Calculator

99%+ purity, HPLC verified. CoA available on request. Domestic AU dispatch.